Membrane Systems

Tangential Flow Filtration System (TFF)

The Tangential Flow Filtration (TFF) Cassette system offers innovative and versatile solutions for concentrating and purifying proteins, biomolecules, and other macromolecules in biotechnology and pharmaceutical processes. This sophisticated system employs cassette modules containing semi-permeable membranes to achieve tangential flow filtration.

During operation, the feed solution circulates tangentially across the membrane surface, allowing smaller molecules and solvents to pass through while retaining larger molecules and contaminants. This gentle yet effective separation process enables precise control over filtration while facilitating target molecule concentration, buffer exchange, and diafiltration.

The modular design provides exceptional scalability, adaptability, and seamless integration into various process configurations, making it an essential tool in downstream processing for high-value, low-volume products.

Sanitech Engineers produces the latest Tangential Flow Filtration Cassette membrane solutions, with all systems meeting international regulatory standards.

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Key Features:

  • Compact skid-mounted design available in fixed or portable configurations
  • Flameproof and non-flameproof options available
  • Integrated SIP and CIP functionality
  • Minimal hold-up volume for efficient processing
  • All wetted components constructed from SS316L/316, silicon, PTFE, and EPDM materials
  • Available automation capabilities
  • Customizable cassette holders to accommodate selected cassette types

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